Nx Protocol
Nx Vitality — New
Start testosterone care when testing confirms low hormone levels, with a three-month plan built around your symptoms and results.
Understand Your Body.
Explore testosterone care, fertility concerns, and sexual wellbeing with care that starts with you.
Explore your options Hear from our patients ↗
Men’s Health
Hormone balanceSexual wellbeingBody composition
Find your starting point
Men’s Health,
personalized.
Get to know the options. Your clinician helps determine which, if any, fits your health and goals.
Your clinician will arrange any required lab work as part of your treatment plan.
8 products
Nx Protocol
Fertility Focus
Help your body produce more of its own testosterone while keeping fertility in focus, for men with low levels.
Nx Protocol
Hormone Balance
Bring elevated estrogen levels down when they are part of a hormone imbalance, with treatment guided by your symptoms and lab results.
Nx Protocol
Vitality
Help bring back sexual desire and enjoyment when testing confirms low hormone levels, with a treatment routine tailored to you.
Nx Protocol
Nx Vitality — Ongoing
For current Nirvanix patients continuing testosterone care, with three more months of treatment and monitoring tailored to you.
Nx Protocol
Desire
For wanting intimacy again and enjoying a more satisfying sex life, with a treatment option focused on low desire.
Nx Protocol
Confidence
Get and keep a firmer erection when aroused, so you can spend less time worrying about performance and more time enjoying intimacy.
Nx Protocol
Nx Vitality +
A personalized hormone-care plan pairing testosterone support with estrogen management, guided by your symptoms and lab results.
More than a treatment
Connect how you feel with what you know.
Changes in libido, energy, or wellbeing can have more than one cause. A conversation about your symptoms, medical history, and lab results helps put the next step in context.
A fuller picture
Review symptoms alongside medication history, relevant labs, and your personal goals.
Options explained
Understand how treatment forms differ and discuss fertility, monitoring, and other considerations.
A plan to revisit
Follow-up helps assess how you feel, review safety labs, and decide whether care should change.
Research over time
How testosterone research unfolds over time.
From early monitoring to longer-term outcomes: checkpoints from testosterone-gel studies and labeling.
The 1.62% gel label calls for a blood-level check around day 14, then day 28. This is a monitoring milestone, not a deadline for feeling different.
Testosterone gel 1.62% · Dosing and monitoring label ↗ (opens in a new tab)In a 227-man trial, sexual-function scores improved from baseline by day 30 with testosterone gel or patches. Both groups received testosterone; there was no placebo group.
Wang et al. · Testosterone gel trial, 2000 ↗ (opens in a new tab)The same trial found gains in lean mass and leg strength by day 90. It studied 1% gel at 50–100 mg daily against a testosterone patch, not compounded cream or injections.
Wang et al. · Testosterone gel trial, 2000 ↗ (opens in a new tab)Among men with anemia and low testosterone in TRAVERSE, 41% with six-month measurements had anemia corrected with 1.62% gel, versus 27.5% with placebo. This was a specific clinical subgroup.
TRAVERSE anemia study · JAMA Network Open, 2023 ↗ (opens in a new tab)In the Testosterone Trials, men 65 and older with low levels had modest sexual-function benefits with 1% gel versus placebo over one year. The main vitality measure did not significantly improve.
Testosterone Trials · NEJM, 2016 ↗ (opens in a new tab)
These checkpoints combine different studies and gel labeling, not one person's expected journey. Findings do not establish the same timing or results for compounded cream or cypionate injections. Your clinician sets monitoring and reviews benefits, side effects, and whether to continue.
A little more understanding
Care informed by the whole study.
Hormone research helps frame a conversation about your symptoms, testing, and options.
Hormone balance
87%
Reached normal testosterone levels with adjusted-dose testosterone gel.[1]
Anemia & low testosterone
41%
Had anemia corrected after six months of testosterone gel treatment.[2]
Separate testosterone-gel studies in men with hypogonadism. Findings do not establish the same outcomes for compounded cream or injections. Individual responses vary, and treatment requires clinical monitoring.
Study details & sources
Hormone balance
At day 180, 87% of 129 appropriately titrated men with hypogonadism and sufficient data had average serum testosterone within the normal range. AndroGel 1%, 50–100 mg daily; an active-comparator study, not a placebo response estimate. Normalization is a laboratory endpoint, not proof of symptom improvement or identical results with compounded cream or cypionate injections.
AndroGel 1% · Clinical studies, section 14.1 (opens in a new tab)Anemia & low testosterone
41.0% (143/349) versus 27.5% (103/375) with placebo among men with available six-month measurements. The TRAVERSE analysis began with 815 men with anemia, hypogonadism, and cardiovascular disease or risk. Daily 1.62% gel; not a general anemia treatment or evidence of identical outcomes with other formulations.
TRAVERSE · JAMA Network Open, 2023 (opens in a new tab)
The details, side by side
Find the option to discuss.
Compare ingredients, forms, and prices before you begin your assessment.
| Treatment | Form / plan | Price & billing | Explore |
|---|---|---|---|
Nx Vitality — NewFirst Time - Mens TRT/HRT 3 Month Plan - Injection | Injection · 3-month plan | Price pending | View option ↗ |
Fertility FocusMen's Hormones – Fertility (Clomiphene) - Oral - 3 Month Supply | Oral treatment · 3-month supply | Price pending | View option ↗ |
Hormone BalanceMen's Hormones (TRT) – Estrogen Management (Anastrozole) - 3 Month Supply - Oral | Oral treatment · 3-month supply option | Price pending | View option ↗ |
VitalityMen's Hormones (TRT) – Testosterone Cream | Topical cream | Price pending | View option ↗ |
Nx Vitality — OngoingOngoing Treatment - Mens TRT/HRT 3 Month Plan - Injection | Injection · 3-month plan | Price pending | View option ↗ |
DesireSexual Health – Desire (PT-141) - Nasal Spray | Nasal spray | Price pending | View option ↗ |
ConfidenceSexual Health – Tadalafil (Daily / Low Dose) - 3 Month Supply - Oral | Oral treatment · Daily / low-dose option | Price pending | View option ↗ |
Nx Vitality +Testosterone Cypionate (Injection) and Anastrazole (Oral) - 3 Month Plan | Injection + oral · 3-month plan | Price pending | View option ↗ |
Prices and eligibility may vary. Final fees and billing terms are shown before payment. Your clinician determines whether treatment is appropriate.
How we work
Your next chapter
starts with you.
Tell us about yourself
Choose a treatment and complete its assessment when enrollment is available.
Connect with a clinician
Review your options, including any labs or video visit needed for a decision.
Follow your personal plan
If prescribed, begin treatment and stay connected through your patient portal.
Nirvanix Health
Personal care.
Part of your everyday.
The Nirvanix community
Care that feels personal.
A few words from the people who know us best.
Loading patient reviews.
The people behind Nirvanix
A personal approach to care.
Meet our founder and members of the Nirvanix clinical team. Your online clinician is assigned according to your treatment and state.
Founder
Shane Ali, MD
A board-certified emergency medicine physician who founded Nirvanix Health in Austin.
Physician Assistant
Allie
A physician assistant with experience in emergency medicine and a focus on listening to patient concerns.
Registered Nurse
Julia Freudenberger
A registered nurse with experience in emergency medicine and mental health.
Questions about men’s health
No. Low energy, changes in libido, and changes in body composition can have several causes. A clinician reviews your symptoms, medications, and medical history before deciding which tests could help. For testosterone deficiency, symptoms and consistently low blood testosterone levels are both part of the diagnosis.
Bloodwork is part of evaluating suspected testosterone deficiency and monitoring treatment. A low testosterone result generally needs confirmation with another morning blood test. Share any recent results, including the collection date and time; your clinician decides what needs repeating or adding.
Yes—bring it up before choosing treatment, even if your plans are further ahead. Testosterone treatment can suppress sperm production and is not recommended for men planning fertility in the near term. Ask your clinician how your options fit those plans.
Compare the ingredient as well as the form: the products listed here are not all versions of the same medicine. Use the options on a treatment page to review related choices, then discuss the routine, monitoring, and risks with your clinician. A different form may require a different prescription and dose.
Track the symptoms you wanted to address, any side effects, and whether the treatment routine works for you. Keep the lab and follow-up appointments your clinician recommends. How you feel and the monitoring results both inform whether to continue or adjust treatment.
Yes. Share what has changed, when it started, and what you want help with in your assessment. You can also explore Sexual Health for more options to discuss with your clinician.
Your next step
Start with what
matters to you.
A little context can help you find a clearer direction.
Find my starting point ↗